journal article·2021-06Open access

Cover Feature: Polydopamine‐Mediated Surface Functionalization of Exosomes (ChemNanoMat 6/2021)

Chenyu Wang, Kenta Kimura, Jincai Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima

ChemNanoMat· Volume 7· Issue 6

Abstract

Exosomes were non-covalently functionalized using the self-polymerization of dopamine and subsequent PEGylation via Thiol-Michael addition. This rapid and versatile exosome coating method improved the colloidal stability of exosomes and endowed them with tunable fluorescence and coating thickness. Collectively, this aggregation-free non-covalent coating approach expands the potential of exosomes in various applications without requiring complex equipment or reagents. More information can be found in the Communication by Hirotaka Ejima et al.
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Research context

OpenAlex topics: Polymer Surface Interaction Studies

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Affiliations

Department of Materials Engineering, Graduate School of Engineering The University of Tokyo 7-3-1 Hongo Bunkyo-ku 113-8656 Japan

Center for Disease Biology and Integrative Medicine, Graduate School of Medicine The University of Tokyo 7-3-1 Hongo Bunkyo-ku 113-8656 Japan

References

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