One step copper oxide (CuO) thin film deposition for non-enzymatic electrochemical glucose detection

Abstract CuO nanoparticle functionalized thin film electrode has been fabricated on fluorine doped tin oxide coated conductive glass using an efficient facile solution deposition technique for non-enzymatic electrochemical detection of glucose. The CuO nanoparticulate thin film exhibited an excellent electrochemical response towards glucose oxidation, high sensitivity of 1207 µA mM−1 cm−2, a linear range of up to 2,2 mM, and fast response of less than 4 s at a potential of 0,55 V vs Ag/AgCl with a limit of detection calculated to be 1,19 µM (at a signal-to-noise ratio (S/N) of 3). The prepared sensor exhibited exceptional selectivity to multiple interference species, satisfactory reproducibility and excellent chemical stability. The performance demonstrated makes the electrode material promising for the development of effective non-enzymatic glucose sensor.