Inorganic Antimicrobial Materials
Source abstract
Abstract
Infectious diseases caused by various pathogens pose a major threat throughout human history. While antibiotics have saved many lives from infections, the rise of antibiotic resistance has reduced their effectiveness. Before the advent of antibiotics, metals were used as antimicrobial agents. Metals and other inorganic materials exhibit broad-spectrum antimicrobial activity through mechanisms distinct from traditional antibiotics, and are capable of killing antibiotic-resistant strains. In this article, we review various inorganic antimicrobial materials and their mechanisms of action, and discuss potential strategies to combat antibiotic resistance.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Antimicrobial agents and applications · Orthopedic Infections and Treatments · Biopolymer Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Innovation and Research
King Faisal Specialist Hospital & Research Centre
Institute of Sustainability for Chemicals, Energy and Environment (ISCE2)
Agency for Science, Technology and Research (A*STAR)
Funding
National Research Foundation Singapore · King Faisal Specialist Hospital and Research Centre
References (100+)
Show source-provided references
1. 10.3390/nano1002029210.3390/nano10020292 ↗
2. 10.1186/s12915-017-0433-z10.1186/s12915-017-0433-z ↗
3. 10.1111/j.1476-5381.2011.01250.x10.1111/j.1476-5381.2011.01250.x ↗
4. 10.2147/IDR.S17386710.2147/IDR.S173867 ↗
5. 10.3390/healthcare1113194610.3390/healthcare11131946 ↗
6. 10.1016/j.jiph.2021.10.02010.1016/j.jiph.2021.10.020 ↗
7. 10.1021/acsinfecdis.4c0011510.1021/acsinfecdis.4c00115 ↗
8. 10.1016/S0140-6736(21)02724-010.1016/S0140-6736(21)02724-0 ↗
9. WHO · 2014
10. 10.3390/ph1611161510.3390/ph16111615 ↗
11. 10.1038/s44259-024-00046-310.1038/s44259-024-00046-3 ↗
12. 10.1038/nrmicro241510.1038/nrmicro2415 ↗
13. 10.1038/nrmicro302810.1038/nrmicro3028 ↗
14. 10.1016/j.ajps.2019.03.00210.1016/j.ajps.2019.03.002 ↗
15. 10.1007/s00253005145710.1007/s002530051457 ↗
16. 10.1089/sur.2008.994110.1089/sur.2008.9941 ↗
17. Dollwet H. H. A. · Trace Elem. Med. · 1985 · 2 · 80
18. 10.1007/BF0190161010.1007/BF01901610 ↗
19. 10.1007/BF0197779310.1007/BF01977793 ↗
20. 10.1002/adhm.20170150310.1002/adhm.201701503 ↗
21. 10.1007/s10904-023-02935-y10.1007/s10904-023-02935-y ↗
22. 10.1016/S0140-6736(01)09037-710.1016/S0140-6736(01)09037-7 ↗
23. 10.1001/jama.1920.0262046002300810.1001/jama.1920.02620460023008 ↗
24. 10.1126/science.ns-13.312.6210.1126/science.ns-13.312.62 ↗
25. 10.1111/1751-7915.1278510.1111/1751-7915.12785 ↗
26. 10.1002/anie.20221734510.1002/anie.202217345 ↗
27. 10.1039/D3NA00530E10.1039/D3NA00530E ↗
28. 10.1021/acsnano.2c0226910.1021/acsnano.2c02269 ↗
29. 10.1016/j.envres.2021.11237310.1016/j.envres.2021.112373 ↗
30. 10.1039/C7CS00748E10.1039/C7CS00748E ↗
31. 10.1016/j.msec.2019.11042110.1016/j.msec.2019.110421 ↗
32. 10.3390/microorganisms1102036910.3390/microorganisms11020369 ↗
33. 10.1021/acsnano.5c0882210.1021/acsnano.5c08822 ↗
34. 10.1016/j.msec.2020.11071210.1016/j.msec.2020.110712 ↗
35. 10.1021/nl301934w10.1021/nl301934w ↗
36. 10.1038/s41429-018-0111-610.1038/s41429-018-0111-6 ↗
37. 10.1128/AAC.00415-1710.1128/AAC.00415-17 ↗
38. 10.1016/j.colsurfb.2016.03.00710.1016/j.colsurfb.2016.03.007 ↗
39. 10.1021/acsanm.3c0561510.1021/acsanm.3c05615 ↗
40. 10.1142/S0219581X2230002410.1142/S0219581X22300024 ↗
41. 10.1007/s10876-022-02304-810.1007/s10876-022-02304-8 ↗
42. 10.1016/j.biomaterials.2011.11.05710.1016/j.biomaterials.2011.11.057 ↗
43. 10.3390/nano1102031210.3390/nano11020312 ↗
44. 10.1016/j.colcom.2024.10080410.1016/j.colcom.2024.100804 ↗
45. 10.1021/acs.bioconjchem.8b0045210.1021/acs.bioconjchem.8b00452 ↗
46. 10.1021/acs.biomac.9b0039210.1021/acs.biomac.9b00392 ↗
47. Zhang Q.-Y. · Mil. Med. Res. · 2021 · 8 · 48
48. 10.1111/jam.1368110.1111/jam.13681 ↗
49. 10.1021/acsnano.0c1075610.1021/acsnano.0c10756 ↗
50. 10.1007/s12011-021-02812-010.1007/s12011-021-02812-0 ↗
51. 10.1016/j.jdent.2017.04.00710.1016/j.jdent.2017.04.007 ↗
52. 10.1016/j.matlet.2019.12681310.1016/j.matlet.2019.126813 ↗
53. 10.1016/j.fct.2022.11336710.1016/j.fct.2022.113367 ↗
54. 10.1007/s13213-010-0015-610.1007/s13213-010-0015-6 ↗
55. 10.1021/acsomega.2c0525210.1021/acsomega.2c05252 ↗
56. 10.1088/0957-4484/25/13/13510110.1088/0957-4484/25/13/135101 ↗
57. 10.1021/acs.chemrev.5b0070310.1021/acs.chemrev.5b00703 ↗
58. 10.1021/ja806804u10.1021/ja806804u ↗
59. 10.1002/adma.20190606310.1002/adma.201906063 ↗
60. 10.1021/acsnano.9b0453310.1021/acsnano.9b04533 ↗
61. 10.1038/s41565-019-0527-610.1038/s41565-019-0527-6 ↗
62. 10.3390/molecules2913311710.3390/molecules29133117 ↗
63. 10.1016/j.saa.2011.10.03810.1016/j.saa.2011.10.038 ↗
64. 10.1016/j.ccr.2016.09.00110.1016/j.ccr.2016.09.001 ↗
65. 10.1039/D0SC04620E10.1039/D0SC04620E ↗
66. 10.3390/molecules2907157410.3390/molecules29071574 ↗
67. 10.1021/acsnano.1c0260210.1021/acsnano.1c02602 ↗
68. 10.1186/s12951-023-02208-310.1186/s12951-023-02208-3 ↗
69. 10.1021/acsnano.3c1304410.1021/acsnano.3c13044 ↗
70. 10.1002/agt2.66610.1002/agt2.666 ↗
71. 10.1038/s41467-024-53537-210.1038/s41467-024-53537-2 ↗
72. 10.1021/acsanm.3c0143210.1021/acsanm.3c01432 ↗
73. 10.1039/D1TB02646A10.1039/D1TB02646A ↗
74. 10.1007/s00253-023-12364-z10.1007/s00253-023-12364-z ↗
75. Clark R. · 2015
76. 10.2174/157341371966623012010333510.2174/1573413719666230120103335 ↗
77. 10.3390/pharmaceutics1503097010.3390/pharmaceutics15030970 ↗
78. 10.1007/s00449-023-02878-110.1007/s00449-023-02878-1 ↗
79. 10.1016/j.jhazmat.2022.12843610.1016/j.jhazmat.2022.128436 ↗
80. 10.3389/fphy.2021.64148110.3389/fphy.2021.641481 ↗
81. Huang S. · 2023 · 24110.1016/B978-0-323-85791-8.00003-3 ↗
82. 10.3389/fmicb.2018.0121810.3389/fmicb.2018.01218 ↗
83. 10.3389/fbioe.2025.160818810.3389/fbioe.2025.1608188 ↗
84. 10.1002/adfm.20251153010.1002/adfm.202511530 ↗
85. 10.3390/biomedicines1102041310.3390/biomedicines11020413 ↗
86. 10.1016/j.pmpp.2023.10202310.1016/j.pmpp.2023.102023 ↗
87. 10.1016/j.colsurfa.2023.13303310.1016/j.colsurfa.2023.133033 ↗
88. 10.3390/jfb1304027410.3390/jfb13040274 ↗
89. 10.1016/j.cis.2021.10247510.1016/j.cis.2021.102475 ↗
90. 10.1016/j.cis.2025.10362610.1016/j.cis.2025.103626 ↗
91. 10.1016/j.ccr.2017.05.00510.1016/j.ccr.2017.05.005 ↗
92. 10.1002/adfm.20191002110.1002/adfm.201910021 ↗
93. 10.1093/jac/dkn03410.1093/jac/dkn034 ↗
94. 10.1080/08927014.2015.104868610.1080/08927014.2015.1048686 ↗
95. 10.1021/acsami.9b2177710.1021/acsami.9b21777 ↗
96. 10.1038/s41570-023-00463-410.1038/s41570-023-00463-4 ↗
97. 10.1016/j.mib.2023.10234710.1016/j.mib.2023.102347 ↗
98. 10.1038/s41467-020-18939-y10.1038/s41467-020-18939-y ↗
99. 10.1021/acsinfecdis.9b0010010.1021/acsinfecdis.9b00100 ↗
100. 10.1021/acsinfecdis.1c0028010.1021/acsinfecdis.1c00280 ↗