Structure and antibacterial performance of silver-supported mesoporous silica antibacterial agent

Owing to special channels of mesoporous silica SBA-15,a novel silver-supported mesoporous silica antibacterial agent(Ag/SBA-15) was synthesized by one-step method with adding Ag into the process of preparing mesoporous carrier.Ag/SBA-15 structure was characterized by X-ray diffraction(XRD),transmission electron microscopy(TEM),electron spectroscopy(EDS),atomic absorption spectrometry(AAS) and N2 adsorption-desorption isotherm.And the antibacterial property of Ag/SBA-15 against Bacillus coli and Staphylococcus aureus was also studied.The results showed that the prepared antibacterial agent with the content of Ag accounting to 14.8% still remained an ordered mesoporous structure with Ag evenly dispersing in the mesoporous carrier and possessed good controlled release behavior.Meanwhile,Ag/SBA-15 antibacterial agent was shown to be an effective bactericide against Bacillus coli and Staphylococcus aureus even with the minimal inhibitory concentration(MIC) of 40 μg/mL,indicating that it has good antibacterial effect.