Preparation of PLLA/FU composite nanofiber film
Source abstract
Abstract
In order to develop one kind of fiber film with sustained drug delivery,poly(L-lactic acid)/flurouracil(PLLA/FU) composite nanofiber film were prepared by electrospinning.The influence of mass fraction of PLLA and relative ratios of fluorouracil on the morphology of the composite nanofibers was discussed.The mechanical properties and surface wettability were also studied.The results showed the diameter of the composite nanofibers increased with the increase of PLLA mass fraction,whereas their diameter decreased with the increase of ratio of fluorouracil.The mechanical performance test showed the tensile strength,rupture work and breaking strength of the composite nanofiber film decreased with the increase of mass fraction of the added drug.The wetting property test showed the wettability of the composite nanofiber film increased with the increase of mass fraction of the added drug,but their heterogeneity was also increased.
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Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · biodegradable polymer synthesis and properties · Dental Implant Techniques and Outcomes
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