Determination of triclosan and triclocarban in textiles by solid-phase extraction and liquid chromatography wave-mass spectrometry tandem

A method for simultaneous determination of triclosan and triclocarban in textiles was developed by solid phase extraction and liquid chromatography-mass spectrometry( SPE-LC-MS / MS). The sample was extracted with dichloromethane by ultrasonic wave and purified on a C18SPE cartridge. The analyte was determined by an electrospray ionization-mass spectrometry in multiple reactions monitoring( MRM) mode. The qualitative and quantitative analyses were based on the retention times and characteristic ion pairs consisting of one parent ion and fragment ions of the analyte. Linearities for triclosan and triclocarban were in the range of 1. 0-50. 0 and 0. 25-50. 0 ng / mL,respectively. The limits of quantification( LOQs) for triclosan and triclocarban were 1. 0 and 0. 25 μg / kg,respectively, and the average recoveries were in the range of 84. 5%-108. 2% with the relative standard deviations below 8. 1%. This method is accurate and sensitive,and is suitable for the analysis of triclosan and triclocarban in textiles.