article·2010-01-01

Preparation and sterilization of quaternary ammonium cationic monomer DBPMA

Xun Zhu

Abstract

A new monomer named quaternary cation N,N-dimethyl,N-benzyl,N-acrylate ammonium chloride(DBPMA) is prepared from acryloyl chloride ethanol dimethylamine and benzyl chloride.The effects of the mole ratio of materials,reaction temperature,reaction time,and solvent on the yield were discussed.In the best reaction conditions,the yield of DBPMA is 82.1%.The bactericidal activity on ATCC6538 bacteria of DBPMA were also studied.The results show that the bactericidal activity of DBPMA is better than that of bactericide 1227.At 25 ℃,the critical micelle concentration(CMC) of DBPMA is much lower than that of dodecyl trimethyl ammonium bromide(DTAB).
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Research context

OpenAlex topics: Antimicrobial agents and applications · Synthesis of β-Lactam Compounds · Chemical Synthesis and Reactions

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