journal article·2025-07-01

Stem Cell-Derived Extracellular Vesicles in Skin Antiaging Treatments

Ji Yeong Park, Se Young Jung, Donghyeon Yoo, Sihun Lee, Dabin Go, Van Dat Bui, Won-Kyo Jung, Dong Gil You, Jae Hyung Park, Wooram Um

ACS Nano· Volume 19· Issue 25
Publisher page

Abstract

As the median age of the global population rises and the demand for aesthetic enhancement increases, interest in antiaging skin technologies has been growing significantly. This review first addresses the molecular mechanisms underlying skin aging, followed by an overview of traditional antiaging approaches and their benefits and limitations. Furthermore, it emphasizes the potential of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) as promising alternatives to address the shortcomings of conventional strategies. This article highlights the antiaging effects and therapeutic mechanisms of MSC-EVs in the skin microenvironment and identifies promising targets for skin antiaging interventions based on the functional properties of MSC-EVs. Finally, this review introduces the recent advances and future directions for MSC-EV-based antiaging strategies.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Extracellular vesicles in disease · Mesenchymal stem cell research · RNA Interference and Gene Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biotechnology, College of Fisheries Science

Pukyong National University

School of Chemical Engineering, College of Engineering

Sungkyunkwan University (SKKU)

Vinmec Research Institute of Stem Cell and Gene Technology, College of Health Sciences, VinUniversity, Vinhomes Ocean Park, Gia Lam District, Hanoi 1310, Vietnam

Marine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities

Department of Chemical Engineering and Biotechnology

Tech University of Korea

Funding

Pukyong National University · National Research Foundation of Korea · Tech University of Korea

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