On-Demand Aligned DNA Hydrogel Via Light Scanning
Source abstract
Abstract
DNA is an anisotropic, water-attracting, and biocompatible material, an ideal building block for hydrogel. The alignment of the anisotropic DNA chains is essential to maximize hydrogel properties, which has been little explored. Here, we present a method to fabricate the anisotropic DNA hydrogel that allows precise control for the polymerization process of photoreactive cationic monomers. Scanning ultraviolet light enables the uniaxial alignment of DNA chains through the polymerization-induced diffusive mass flow using a concentration gradient. While studying anisotropic mechanical properties and orientation recovery according to the DNA chain alignment direction, we demonstrate the potential of directionally controlled DNA hydrogels as smart materials.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · RNA Interference and Gene Delivery · Biosensors and Analytical Detection
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea
Center for Integrated Nanotechnologies, Los Alamos National Laboratory, Los Alamos 87545, New Mexico, USA
Chemical Materials Solutions Center, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea
Graduate School of Nanoscience and Technology, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea
Department of Chemical and Biomolecular Engineering, Cornell University, Ithaca 14853, New York, USA
Funding
Ministry of Trade, Industry and Energy · National Research Foundation
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