journal article·2026-01

Surface-engineered taurine-doped polyaniline nanofibers with enhanced electrical and antioxidant properties for neural tissue engineering applications

Zohreh Daraeinejad, Banafsheh Dolatyar, Iman Shabani, Ehsan Seyedjafari

Synthetic Metals· Volume 316
Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Conducting polymers and applications · Polymer composites and self-healing

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (79)

Show source-provided references
1. Biological characteristics of tissue engineered-nerve grafts enhancing peripheral nerve regeneration10.1186/s13287-024-03827-9 ↗
2. Advances in biomaterial-based tissue engineering for peripheral nerve injury repair
3. Strategies and prospects of effective neural circuits reconstruction after spinal cord injury10.1038/s41419-020-2620-z ↗
4. Stem cell transplantation: a promising therapy for spinal cord injury10.2174/1574888X14666190823144424 ↗
5. Thinking about the nerve impulse: a critical analysis of the electricity-centered conception of nerve excitability10.1016/j.pneurobio.2018.06.009 ↗
6. Electrically active biomaterials for stimulation and regeneration in tissue engineering10.1002/jbm.a.37871 ↗
7. The role of peripheral nerve ECM components in the tissue engineering nerve construction
8. Trends in the design of nerve guidance channels in peripheral nerve tissue engineering10.1016/j.pneurobio.2015.06.001 ↗
9. Tissue engineering of the nervous system
10. Electrical stimulation to promote peripheral nerve regeneration10.1177/1545968315604399 ↗
11. Conducting polymers for tissue regeneration in vivo10.1021/acs.chemmater.0c00767 ↗
12. A self-powered nerve conduit based on zinc-oxygen battery accelerates nerve cell growth10.1016/j.colsurfa.2025.137225 ↗
13. Conductive polymers and hydrogels for neural tissue engineering10.1007/s41745-019-00126-8 ↗
14. Saberi · Electr. Conduct. Mater. Oppor. Chall. Tissue Eng. · 2019 · 9 · 448
15. Conducting polymers for tissue engineering10.1021/acs.biomac.8b00276 ↗
16. Tissue engineering of electrically responsive tissues using polyaniline based polymers: a review10.1016/j.biomaterials.2014.07.020 ↗
17. Progress in conductive polyaniline-based nanocomposites for biomedical applications: a review10.1021/acs.jmedchem.9b00803 ↗
18. The biocompatibility of polyaniline and polypyrrole: a comparative study of their cytotoxicity, embryotoxicity and impurity profile10.1016/j.msec.2018.05.037 ↗
19. Oriented polyaniline/poly-l-lactic acid/gelatin nanofiber scaffolds promote outgrowth of spiral ganglion neurons10.1002/jbm.a.37649 ↗
20. Biocompatibility of polyaniline10.1016/j.synthmet.2012.02.024 ↗
21. Exploring the critical factors limiting polyaniline biocompatibility10.3390/polym11020362 ↗
22. Enhancing biocompatibility of polyaniline-based scaffolds by using a bioactive dopant10.1016/j.synthmet.2020.116642 ↗
23. Tailor-made conductive PANI-coated nanofibers for tissue engineering applications10.1016/j.synthmet.2022.117049 ↗
24. Emergence of taurine as a therapeutic agent for neurological disorders10.4103/1673-5374.374139 ↗
25. Taurine as an essential neuromodulator during perinatal cortical development10.3389/fncel.2017.00328 ↗
26. M.C. Shivaraj, G. Marcy, G. Low, J.R. Ryu, X. Zhao, F.J. Rosales, E.L. Goh, Taurine induces proliferation of neural stem cells and synapse development in the developing mouse brain, (2012).10.1371/journal.pone.0042935 ↗
27. Epidermal growth factor promotes the differentiation of stem cells derived from human umbilical cord blood into neuron-like cells via taurine induction in vitro10.1007/s11626-009-9184-7 ↗
28. Retinoic acid and taurine enhance differentiation of the human bone marrow stem cells into cone photoreceptor cells and retinal ganglion cells10.1002/jcb.30151 ↗
29. Neural tissue engineering: the influence of scaffold surface topography and extracellular matrix microenvironment10.1039/D0TB01605E ↗
30. Biocompatible EDOT–Pyrrole conjugated conductive polymer coating for augmenting cell attachment, activity, and differentiation10.1021/acsabm.4c01647 ↗
31. Electrically conductive coatings in tissue engineering10.1016/j.actbio.2024.08.007 ↗
32. Accelerated epidermal regeneration and improved dermal reconstruction achieved by polyethersulfone nanofibers10.1089/ten.tea.2009.0829 ↗
33. Optimal electrical stimulation boosts stem cell therapy in nerve regeneration10.1016/j.biomaterials.2018.07.015 ↗
34. Electrical stimulation promotes stem cell neural differentiation in tissue engineering
35. Polypyrrole-coated electrospun poly (lactic acid) fibrous scaffold: effects of coating on electrical conductivity and neural cell growth10.1080/09205063.2014.926578 ↗
36. A review on electrospun polymeric nanofibers: production parameters and potential applications10.1016/j.polymertesting.2020.106647 ↗
37. Effect of dopant type on the properties of polyaniline10.1002/app.29708 ↗
38. High performance nanofiber-supported thin film composite forward osmosis membranes based on continuous thermal-rolling pretreated electrospun PES/PAN blend substrates10.1016/j.chemosphere.2020.127687 ↗
39. Optimisation of polyethersulfone/polyaniline blended membranes using response surface methodology approach10.1016/j.desal.2012.11.033 ↗
40. Preparation and characterization of a polyethersulfone/polyaniline nanocomposite membrane for ultrafiltration and as a substrate for a gas separation membrane10.1039/C4RA16951D ↗
41. Controlling the porosity of fibrous scaffolds by modulating the fiber diameter and packing density10.1002/jbm.a.33010 ↗
42. Biocompatible and electroconductive polyaniline-based biomaterials for electrical stimulation10.1016/j.eurpolymj.2018.08.036 ↗
43. Advances in polyaniline for biomedical applications10.2174/0929867328666210419135519 ↗
44. Influence of dopant on electroactivity of polyaniline
45. Electrical stimulation of nerve cells using conductive nanofibrous scaffolds for nerve tissue engineering10.1089/ten.tea.2008.0689 ↗
46. Synthesis and optical characterization of benzene sulfonic acid doped polyaniline
47. Biocompatible novel starch/polyaniline composites: characterization, anti-cytotoxicity and antioxidant activity10.1016/j.colsurfb.2010.07.005 ↗
48. Biodegradable polyaniline/dextrin conductive nanocomposites: synthesis, characterization, and study of antioxidant activity and sorption of heavy metal ions10.1007/s13726-014-0221-3 ↗
49. Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production10.1007/s00726-011-0962-7 ↗
50. Taurine, homotaurine, GABA and hydrophobic amino acids content influences “in vitro” antioxidant and SIRT1 modulation activities of enzymatic protein hydrolysates from algae10.1038/s41598-022-25130-4 ↗
51. Polyphenols as a versatile component in tissue engineering10.1016/j.actbio.2020.11.004 ↗
52. Repositioning natural antioxidants for therapeutic applications in tissue engineering10.3390/bioengineering7030104 ↗
53. Synergistic effects of conductive PVA/PEDOT electrospun scaffolds and electrical stimulation for more effective neural tissue engineering10.1016/j.eurpolymj.2020.110051 ↗
54. Enhanced adhesion and proliferation of human umbilical vein endothelial cells on conductive PANI-PCL fiber scaffold by electrical stimulation10.1016/j.msec.2016.11.052 ↗
55. C.E. Schmidt, electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials10.1016/S0142-9612(00)00344-6 ↗
56. Taurine stimulates proliferation of mice embryonic cultured neural progenitor cells10.1002/jnr.22328 ↗
57. Multiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse10.1016/j.scr.2014.02.009 ↗
58. Enhanced cardiac differentiation of human cardiovascular disease patient-specific induced pluripotent stem cells by applying unidirectional electrical pulses using aligned electroactive nanofibrous scaffolds10.1021/acsami.6b15271 ↗
59. Enhancing cellular infiltration on fluffy polyaniline-based electrospun nanofibers10.3389/fbioe.2021.641371 ↗
60. Highly porous electrospun nanofibers enhanced by ultrasonication for improved cellular infiltration10.1089/ten.tea.2010.0709 ↗
61. Effects of electrical stimulation on cell proliferation and apoptosis10.1002/jcp.25975 ↗
62. Taurine stimulates proliferation and promotes neurogenesis of mouse adult cultured neural stem/progenitor cells10.1016/j.scr.2012.02.004 ↗
63. Antimicrobial activity and cytotoxicity of cotton fabric coated with conducting polymers, polyaniline or polypyrrole, and with deposited silver nanoparticles10.1016/j.apsusc.2016.11.024 ↗
64. Polyaniline–maghemite based dispersion: electrical, magnetic properties and their cytotoxicity10.1016/j.synthmet.2016.01.010 ↗
65. Taurine in development10.1152/physrev.1993.73.1.119 ↗
66. Taurine resumed neuronal differentiation in arsenite-treated N2a cells through reducing oxidative stress, endoplasmic reticulum stress, and mitochondrial dysfunction10.1007/s00726-014-1901-1 ↗
67. A tailored polylactic acid/polycaprolactone biodegradable and bioactive 3D porous scaffold containing gelatin nanofibers and taurine for bone regeneration10.1038/s41598-020-70155-2 ↗
68. Injectable taurine-loaded alginate hydrogels for retinal pigment epithelium (RPE) regeneration10.1016/j.msec.2019.109787 ↗
69. Characterization of taurine/silk fibroin blend film for application as a carrier for corneal endothelial cell transplantation10.1007/s13233-022-0033-9 ↗
70. Electrical stimulation affects neural stem cell fate and function in vitro10.1016/j.expneurol.2019.112963 ↗
71. Unraveling the mechanistic effects of electric field stimulation towards directing stem cell fate and function: a tissue engineering perspective10.1016/j.biomaterials.2017.10.003 ↗
72. Extremely low-frequency electromagnetic fields promote in vitro neurogenesis via upregulation of Cav1-channel activity10.1002/jcp.21293 ↗
73. Electrical stimulation promotes stem cell neural differentiation in tissue engineering10.1155/2021/6697574 ↗
74. Conductive biomaterials as substrates for neural stem cells differentiation towards neuronal lineage cells10.1002/mabi.202000123 ↗
75. Graphene-based conductive fibrous scaffold boosts sciatic nerve regeneration and functional recovery upon electrical stimulation
76. Directed neural stem cell differentiation on polyaniline-coated high strength hydrogels10.1016/j.mtchem.2016.10.002 ↗
77. Electrospun conducting polymer nanofibers and electrical stimulation of nerve stem cells10.1016/j.jbiosc.2011.07.010 ↗
78. Electrically conductive materials: opportunities and challenges in tissue engineering10.3390/biom9090448 ↗
79. Engineering 2D approaches fibrous platform incorporating turmeric and polyaniline nanoparticles to predict the expression of βIII-Tubulin and TREK-1 through qRT-PCR to detect neuronal differentiation of PC12 cells10.1016/j.msec.2021.112176 ↗