journal article·2017-08-22

Versatile DNA Origami Nanostructures in Simplified and Modular Designing Framework

Yan Cui, Ruipeng Chen, Mingxuan Kai, Yaqi Wang, Yongli Mi, Bryan Wei

ACS Nano· Volume 11· Issue 8
Publisher page

Abstract

We introduce a simplified and modular architecture for design and construction of complex origami nanostructures. A series of basic two-dimensional and three-dimensional structures are presented. As the resulting structures can be virtually divided into blocks, modular remodeling such as translocation, contraction/extension, and bending is carried out. Structures under such a designing framework are morphable. Local conformational changes can propagate to the entire structure to reshape the global conformation.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · RNA Interference and Gene Delivery · Biosensors and Analytical Detection

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Affiliations

School of Life Sciences, Tsinghua University−Peking University Center for Life Sciences, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China

Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong SAR

School of Chemical Science and Engineering, Tongji University, Shanghai 200092, China

Funding

Research Grants Council, University Grants Committee · National Natural Science Foundation of China

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