Silver Nanoparticle-Immobilized Schiff-Base Macrocycles as Nanozymes with Peroxidase Mimic Activity for Antibacterial Films

Kuiyuan Wang; Carl Redshaw; Xuesong Zhao; Anheng Wang; Kai Chen; Yuanting Qiao

doi:10.1021/acsanm.4c02258

journal article·2024-07-26Open access

Silver Nanoparticle-Immobilized Schiff-Base Macrocycles as Nanozymes with Peroxidase Mimic Activity for Antibacterial Films

Kuiyuan Wang, Carl Redshaw, Xuesong Zhao, Anheng Wang, Kai Chen, Yuanting Qiao

ACS Applied Nano Materials· Volume 7· Issue 14

Publisher page Open full text

Source abstract

Abstract

The development of nanozymes has emerged as a promising pathway for combating bacterial infections. In this work, Ag/Schiff base nanozymes are obtained through the in situ reduction method on [2 + 3] Schiff base macrocycles using eco-friendly reductant α-tocopherol. The silver prepared was found to be nanoscale by TEM, and Ag NPs grew and dispersed uniformly on the surface of the Schiff base macrocycle due to the abundance of the C═N double bonds. The peroxidase-like catalytic activity of the Ag/Schiff base was evaluated toward 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of H 2 O 2, and the K m values of 0.350 and 0.090 mM confirm the strong affinity of Ag/Schiff base for H 2 O 2 and TMB. Moreover, the nanozyme exhibited good antibacterial properties against Streptococcus sanguinis, Pseudomonas aeruginosa, and Staphylococcus aureus, and in vivo tests confirmed that the Ag/Schiff base had negligible biotoxicity. Benefiting from the good antimicrobial and biosafety properties, the nanozymes were explored to prepare antibacterial films, and the bacterial inhibition zones demonstrated that the introduction of the Ag/Schiff base could prevent the growth of bacteria.

Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials Catalysis & surfaces

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoplatforms for cancer theranostics · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Zhejiang University-Quzhou, No. 99 Zheda Road, Quzhou 324000, P. R. China

Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, P. R. China

Department of Chemistry, University of Hull, Hull HU6 7RX, U.K.

Institute of Chinese Medical Sciences & State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macau 519031, Hong Kong SAR, P. R. China

Zhuhai UM Science and Technology Research Institute, University of Macau, Guangdong 519000, P. R. China

Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control, School of Environmental Science and Engineering, Nanjing University of Information Science & Technology, Nanjing 210044, P. R. China

Department of Chemical Engineering, Swansea University, Bay Campus, Swansea SA1 8EN, U.K.

Funding

Institute of Zhejiang University-Quzhou Foundation

References (48)

Show source-provided references

1. 10.1016/j.cej.2021.12943110.1016/j.cej.2021.129431 ↗

2. 10.1021/acsanm.2c0300910.1021/acsanm.2c03009 ↗

3. 10.1038/s43586-024-00315-510.1038/s43586-024-00315-5 ↗

4. 10.1021/acsanm.4c0104910.1021/acsanm.4c01049 ↗

5. 10.3390/biomimetics805044610.3390/biomimetics8050446 ↗

6. 10.1039/c9cc06211d10.1039/c9cc06211d ↗

7. 10.1016/j.bios.2019.11145010.1016/j.bios.2019.111450 ↗

8. 10.1039/d0cc06925f10.1039/d0cc06925f ↗

9. 10.1002/smll.20220599710.1002/smll.202205997 ↗

10. 10.1021/acsbiomaterials.0c0083110.1021/acsbiomaterials.0c00831 ↗

11. 10.1016/j.snb.2019.12751210.1016/j.snb.2019.127512 ↗

12. 10.1016/j.snb.2020.12802110.1016/j.snb.2020.128021 ↗

13. 10.1039/d2qi02727e10.1039/d2qi02727e ↗

14. 10.1016/j.snb.2023.13360910.1016/j.snb.2023.133609 ↗

15. 10.1016/j.colsurfb.2023.11324810.1016/j.colsurfb.2023.113248 ↗

16. 10.1002/ange.20211617010.1002/ange.202116170 ↗

17. 10.1016/j.chempr.2020.10.02310.1016/j.chempr.2020.10.023 ↗

18. 10.1016/j.nantod.2020.10097110.1016/j.nantod.2020.100971 ↗

19. 10.1002/chem.20210417410.1002/chem.202104174 ↗

20. 10.3390/nano907096110.3390/nano9070961 ↗

21. 10.1016/j.nantod.2022.10142910.1016/j.nantod.2022.101429 ↗

22. 10.1016/j.apcatb.2015.12.05110.1016/j.apcatb.2015.12.051 ↗

23. 10.1016/j.jclepro.2021.12974510.1016/j.jclepro.2021.129745 ↗

24. 10.5101/nbe.v14i4.p367-37410.5101/nbe.v14i4.p367-374 ↗

25. 10.1016/j.colsurfa.2023.13100810.1016/j.colsurfa.2023.131008 ↗

26. 10.1021/acsami.0c1214110.1021/acsami.0c12141 ↗

27. 10.1002/admi.20220092810.1002/admi.202200928 ↗

28. 10.1021/acsami.2c0027810.1021/acsami.2c00278 ↗

29. 10.1016/j.jcis.2020.11.06610.1016/j.jcis.2020.11.066 ↗

30. 10.1016/j.molstruc.2024.13749510.1016/j.molstruc.2024.137495 ↗

31. 10.1016/j.molstruc.2023.13656810.1016/j.molstruc.2023.136568 ↗

32. 10.1016/j.inoche.2023.11179510.1016/j.inoche.2023.111795 ↗

33. 10.1002/smll.20220827610.1002/smll.202208276 ↗

34. 10.1016/j.cej.2022.13503410.1016/j.cej.2022.135034 ↗

35. 10.1002/aoc.747710.1002/aoc.7477 ↗

36. 10.1016/j.ccr.2023.21532610.1016/j.ccr.2023.215326 ↗

37. 10.1021/acsami.1c1979510.1021/acsami.1c19795 ↗

38. 10.1016/j.foodhyd.2022.10830510.1016/j.foodhyd.2022.108305 ↗

39. 10.26434/chemrxiv-2021-rbblr10.26434/chemrxiv-2021-rbblr ↗

40. 10.1039/D0NR03790G10.1039/D0NR03790G ↗

41. 10.1039/C8CC07800A10.1039/C8CC07800A ↗

42. 10.1038/nnano.2007.26010.1038/nnano.2007.260 ↗

43. 10.1039/C7NJ01177F10.1039/C7NJ01177F ↗

44. 10.1016/j.cej.2020.12724010.1016/j.cej.2020.127240 ↗

45. 10.1016/j.snb.2016.07.10610.1016/j.snb.2016.07.106 ↗

46. 10.1016/j.snb.2022.13234310.1016/j.snb.2022.132343 ↗

47. 10.1016/j.colsurfb.2021.11179810.1016/j.colsurfb.2021.111798 ↗

48. 10.1016/j.jclepro.2020.12233910.1016/j.jclepro.2020.122339 ↗