journal article·2019-06-25Open access

Time-Resolved Analysis of the Structural Dynamics of Assembling Gold Nanoparticles

Stefan Merkens, Mohammad Vakili, Ana Sánchez-Iglesias, Lucio Litti, Yunyun Gao, Paul V. Gwozdz, Lewis Sharpnack, Robert H. Blick, Luis M. Liz-Marzán, Marek Grzelczak, Martin Trebbin

ACS Nano· Volume 13· Issue 6

Abstract

The hydrophobic collapse is a structural transition of grafted polymer chains in a poor solvent. Although such a transition seems an intrinsic event during clustering of polymer-stabilized nanoparticles in the liquid phase, it has not been resolved in real time. In this work, we implemented a microfluidic 3D-flow-focusing mixing reactor equipped with real-time analytics, small-angle X-ray scattering (SAXS), and UV-vis-NIR spectroscopy to study the early stage of cluster formation for polystyrene-stabilized gold nanoparticles. The polymer shell dynamics obtained by in situ SAXS analysis and numerical simulation of the solvent composition allowed us to map the interaction energy between the particles at early state of solvent mixing, 30 ms behind the crossing point. We found that the rate of hydrophobic collapse depends on water concentration, ranging between 100 and 500 nm/s. Importantly, we confirmed that the polymer shell collapses prior to the commencement of clustering.
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Research context

OpenAlex topics: Electrohydrodynamics and Fluid Dynamics · Innovative Microfluidic and Catalytic Techniques Innovation · Gold and Silver Nanoparticles Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

CIC nanoGUNE, Tolosa Hiribidea 76, 20018 Donostia - San Sebastián, Spain

The Hamburg Centre for Ultrafast Imaging (CUI), University of Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany

CIC biomaGUNE and CIBER-BBN, Paseo Miramón 182, 20014, Donostia - San Sebastián, Spain

Dipartimento di Scienze Chimiche, Univerisità degli Studi di Padova, Via Marzolo 1, 35131 Padova, Italy

Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany

Center for Hybrid Nanostructures (CHyN), University of Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany

Beamline ID02, The European Synchrotron (ESRF), 71 Avenue des Martyrs, 38043 Grenoble, France

Ikerbasque, Basque Foundation for Science, 48013 Bilbao, Spain

Donostia International Physics Center (DIPC), Manuel Lardizabal Ibilbidea 4, 20018 Donostia - San Sebastián, Spain

Department of Chemistry, The State University of New York at Buffalo, 760 Natural Sciences Complex, Buffalo, New York 14260-3000, United States

Funding

European Commission · Ministerio de Econom?a y Competitividad · Deutsche Forschungsgemeinschaft

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