journal article·2020-08-25

Graphene-Sealed Flow Cells for In Situ Transmission Electron Microscopy of Liquid Samples

Gabriel Dunn, Vivekananda P. Adiga, Thang Pham, Christopher Bryant, Donez J. Horton-Bailey, Jason N. Belling, Ben LaFrance, Jonathan A. Jackson, Hamid Reza Barzegar, Jong Min Yuk, Shaul Aloni, Michael F. Crommie, Alex Zettl

ACS Nano· Volume 14· Issue 8
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Abstract

We introduce a graphene-based nanofluidic cell that facilitates in situ imaging of liquid samples via transmission electron microscopy. The cell combines the benefits of graphene liquid cells-namely, high resolution, reduced charging effects, and excellent sample stability-with the ability to introduce reactants and control fluid concentrations as provided by conventional silicon-nitride-windowed flow cells. The graphene flow cell offers significantly less window bowing compared to existing commercial holders. We demonstrate the performance of the flow cell by imaging gold nanoparticle dynamics and uranyl acetate crystallization. Our results confirm the utility of graphene flow cells in obtaining the high spatial and temporal resolution required for probing the complex dynamics of nanoparticles and nucleation pathways in aqueous solutions.
Source: europepmc · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Advanced Electron Microscopy Techniques and Applications · Electrochemical Analysis and Applications · Electron and X-Ray Spectroscopy Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Physics, University of California at Berkeley, Berkeley, California 94720, United States

Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States

Kavli Energy NanoSciences Institute at the University of California at Berkeley and the Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States

Department of Biochemistry and Molecular Biology, University of California at Berkeley, Berkeley, California 94720, United States

The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States

Funding

Basic Energy Sciences · Defense Threat Reduction Agency · Division of Materials Research

References (25)

Show source-provided references
1. 10.1038/nmat94410.1038/nmat944 ↗
2. Ross F. M. · 201610.1017/9781316337455 ↗
3. 10.1126/science.aaa988610.1126/science.aaa9886 ↗
4. 10.1146/annurev-physchem-040215-11250110.1146/annurev-physchem-040215-112501 ↗
5. 10.1021/nl200285r10.1021/nl200285r ↗
6. 10.1073/pnas.080956710610.1073/pnas.0809567106 ↗
7. 10.1126/science.121765410.1126/science.1217654 ↗
8. 10.1126/science.aah443410.1126/science.aah4434 ↗
9. 10.1016/j.cplett.2016.02.06610.1016/j.cplett.2016.02.066 ↗
10. 10.1021/nl404577c10.1021/nl404577c ↗
11. 10.1038/s41578-018-0071-210.1038/s41578-018-0071-2 ↗
12. 10.1017/S143192761300150510.1017/S1431927613001505 ↗
13. 10.1021/nl104292k10.1021/nl104292k ↗
14. 10.1021/acs.nanolett.8b0249010.1021/acs.nanolett.8b02490 ↗
15. 10.1021/nl402694n10.1021/nl402694n ↗
16. 10.1021/acs.nanolett.6b0438310.1021/acs.nanolett.6b04383 ↗
17. 10.1002/pssb.20160023210.1002/pssb.201600232 ↗
18. 10.1021/acs.nanolett.8b0338810.1021/acs.nanolett.8b03388 ↗
19. 10.1038/ncomms706810.1038/ncomms7068 ↗
20. 10.1021/acs.nanolett.8b0136610.1021/acs.nanolett.8b01366 ↗
21. 10.1021/acs.nanolett.7b0471310.1021/acs.nanolett.7b04713 ↗
22. 10.1021/acs.nanolett.5b0163610.1021/acs.nanolett.5b01636 ↗
23. Adiga, V. P.; Dunn, G.; Zettl, A. K.; Alivisatos, A. P. Liquid Flow Cells Having Graphene on Nitride for Microscopy. US 9449787 B2, 2016.
24. 10.1021/acs.langmuir.5b0015010.1021/acs.langmuir.5b00150 ↗
25. 10.1021/nl070192x10.1021/nl070192x ↗