Highly Sensitive, Tunable Chirality Amplification through Space Visualized for Gold Nanorods Capped with Axially Chiral Binaphthyl Derivatives

-symmetric, axially chiral binaphthyl thiols, preparation of dispersions in the nematic liquid crystal 5CB, measurements of the helical pitch, and the determination of the helical twisting power as well as the average distance between the chiral nanomaterial additives. By comparison to the neat organic chiral derivatives, we demonstrate how the amplification of chirality facilitated by GNRs decorated with chiral molecules can be used to clearly distinguish the chiral induction strength of a homologous series of binaphthyl derivatives, differing only in the length of the nontethered aliphatic chain, in the induced chiral nematic liquid crystal phase. Considering systematic errors in sample preparation and optical measurements, these chiral molecules would otherwise be deemed identical with respect to chiral induction. Notably, we find some of the highest ever-reported values of the helical twisting power. We further support our experimentally derived arguments of a more comprehensive understanding of chirality transfer by calculations of a suitable pseudoscalar chirality indicator.