DataVXACS NanoPaper
journal article·2016-01-26

Nanoscale Electric Permittivity of Single Bacterial Cells at Gigahertz Frequencies by Scanning Microwave Microscopy

Maria Chiara Biagi, Rene Fabregas, Georg Gramse, Marc Van Der Hofstadt, Antonio Juárez, Ferry Kienberger, Laura Fumagalli, Gabriel Gomila

ACS Nano· Volume 10· Issue 1
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Source abstract

Abstract

We quantified the electric permittivity of single bacterial cells at microwave frequencies and nanoscale spatial resolution by means of near-field scanning microwave microscopy. To this end, calibrated complex admittance images have been obtained at ∼19 GHz and analyzed with a methodology that removes the nonlocal topographic cross-talk contributions and thus provides quantifiable intrinsic dielectric images of the bacterial cells. Results for single Escherichia coli cells provide a relative electric permittivity of ∼4 in dry conditions and ∼20 in humid conditions, with no significant loss contributions. Present findings, together with the ability of microwaves to penetrate the cell membrane, open an important avenue in the microwave label-free imaging of single cells with nanoscale spatial resolution.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Near-Field Optical Microscopy · Microwave Imaging and Scattering Analysis · Microwave and Dielectric Measurement Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institut de Bioenginyeria de Catalunya (IBEC), c/Baldiri i Reixac 11-15, 08028 Barcelona, Spain

Institute for Biophysics, Johannes Kepler University Linz, Gruberst. 40, 4020 Linz, Austria

Departament de Microbiologia, Universitat de Barcelona, Av. Diagonal 643, 08028 Barcelona, Spain

Keysight Lab, Keysight Technologies Austria GmbH, Gruberst. 40, 4020 Linz, Austria

School of Physics and Astronomy, University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom

Departament d’Electrònica, Universitat de Barcelona, C/Martí i Franqués 1, 08028 Barcelona, Spain

Funding

Ministerio de Economía y Competitividad · Institució Catalana de Recerca i Estudis Avançats

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