journal article·2007-11-30

Light-Assisted Oxidation of Single-Wall Carbon Nanohorns for Abundant Creation of Oxygenated Groups That Enable Chemical Modifications with Proteins To Enhance Biocompatibility

Minfang Zhang, Masako Yudasaka, Kumiko Ajima, Jin Miyawaki, Sumio Iijima

ACS Nano· Volume 1· Issue 4
Publisher page

Abstract

We show that light-assisted oxidation with hydrogen peroxide effectively and rapidly opens holes in carbon nanohorn walls and, more importantly, creates abundant oxygenated groups such as carboxylic groups at the hole edges. These oxygenated groups reacted with the protein bovine serum albumin. The obtained conjugates were highly dispersed in phosphate-buffered saline and were taken up by cultured mammalian cells via an endocytosis pathway.
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Research context

OpenAlex topics: Carbon Nanotubes in Composites · Graphene and Nanomaterials Applications · Electrochemical sensors and biosensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

SORST-JST, c/o NEC, 34 Miyukigaoka, Tsukuba, Ibaraki 305-8501, Japan

NEC, 34 Miyukigaoka, Tsukuba, Ibaraki 305-8501, Japan

Meijo University, 1-501 Shiogamaguchi, Tenpaku-ku, Nagoya 468-8502, Japan

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