Fabrication of a novel ZnO–CoO/rGO nanocomposite for nonenzymatic detection of glucose and hydrogen peroxide

Abstract Herein, a novel nanocomposite of binary ZnO–CoO nanoparticles loaded on the graphene nanosheets (ZnO–CoO/rGO) has been successfully constructed via a facile, economical and two–step process. The obtained ZnO–CoO/rGO hybrids with high electrical conductivity and abundant active sites, could be modified on a glassy carbon electrode to detect glucose and H 2 O 2 multi–functionally. The fabricated biosensor exhibits wide linear range for glucose (10 μM to 11.205 mM) and H 2 O 2 (25 μM to 11.1 mM), and their corresponding sensitivity are 168.7 μA mM −1 cm −2 and 183.3 μA mM −1 cm −2 . The limits of detection are 1.3 μM and 0.44 μM for the oxidation of glucose and the reduction of H 2 O 2 , respectively. Furthermore, remarkable selectivity, long–term stability and outstanding reproducibility of the non–enzyme biosensor prove that ZnO–CoO/rGO hybrids are the promising candidate in practical applications.