DataVXSmallPaper
journal article·2026-05

Liquid Biopsy Differentiation of Pancreatic Cancer From Non‐Cancerous Pancreatic Disease Using Dielectrophoresis‐Recovered Nanoparticles Carrying Cell‐Free DNA and Protein Biomarkers (Small 29/2026)

Anna Malakian, Augusta Modestino, Jesus Bueno, Archana Machireddy, Jason Ware, Sean Hamilton, Ella Stimson, Sarah Mitchell, Joshua C. Saldivar, Ashley R. Woodfin, Corey M. Dambacher, Kyle Gustafson, Delaney Shea, Srivathsan Ranganathan, Mehrzad Sasanpour, Christian Ross, Dove Keith, Jeong Youn Lim, Xubo Song, Scott M. Lippman, Rosalie Sears, Terry Morgan, Michael Heller, Stuart D. Ibsen

Small· Volume 22· Issue 29
Publisher page
Source abstract

Abstract

Pancreatic Cancer Detection Tumors release extracellular vesicle nanoparticles into circulation which carry important cancer-specific biomarkers. These nanoparticles are readily recovered from undiluted plasma by a microfluidic chip with an array of circular microelectrodes at the bottom that generate dielectrophoretic forces, represented by the curved vertical and horizontal lines. These forces enable on-chip nanoparticle recovery, purification, and biomarker quantification which has diagnostic value and can accurately detect patients with pancreatic cancer. More in the Research Article (e02532), Stuart D. Ibsen and co-workers.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Microfluidic and Bio-sensing Technologies · Extracellular vesicles in disease · Nanopore and Nanochannel Transport Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Cancer Early Detection Advanced Research Center Knight Cancer Institute Oregon Health and Science University Portland Oregon USA

Department of Biomedical Engineering School of Medicine Oregon Health and Science University Portland Oregon USA

Division of Oncological Sciences Knight Cancer Institute Oregon Health and Science University Portland Oregon USA

RyboDyn Inc. San Diego California USA

Brenden‐Colson Center for Pancreatic Care Oregon Health and Science University Portland Oregon USA

Biostatistics Shared Resource Knight Cancer Institute Oregon Health and Science University Portland Oregon USA

Moores Cancer Center University of California San Diego San Diego California USA

Department of Molecular and Medical Genetics Oregon Health and Science University Portland Oregon USA

Knight Cancer Institute Oregon Health and Science University Portland Oregon USA

Pathology & Laboratory Medicine Oregon Health and Science University Portland Oregon USA

References

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