Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation (Small 27/2026)
Source abstract
Abstract
Photodegradable Hydrogels In the Research Article (e09246), Jacopo Di Russo and co-workers present a light-tunable hydrogel platform that enables precise spatial control of extracellular matrix topography. By combining micro engineered substrates with defined mechanical and biochemical cues, the system recreates dynamic microenvironmental changes that stress the retinal pigment epithelium. This platform enables systematic investigation of mechanobiological responses associated with age-related outer retinal pathologies.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Neuroscience and Neural Engineering · Advanced Materials and Mechanics · Hydrogels: synthesis, properties, applications
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Affiliations
Institute of Molecular and Cellular Anatomy RWTH Aachen University Aachen Germany
DWI‐Leibniz‐Institute for Interactive Materials Aachen Germany
Department of Advanced Materials for Biomedicine (AMB) CBMS—Center for Biohybrid Medical Systems AME—Institute of Applied Medical Engineering RWTH Aachen University Aachen Germany
Institute for Technical and Macromolecular Chemistry Chair for Macromolecular Materials for Medicine RWTH Aachen University Aachen Germany
References
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