Light‐Guided Molecular Patterning for High‐Throughput Single‐Molecule Mechanical Characterization (Small 21/2026)
Source abstract
Abstract
Molecular Patterning In the Research Article (e11065), Wesley P. Wong and co-workers illustrate spatially organized, light-responsive oligonucleotides assembled on a solid substrate with high programmability. UV illumination patterns are projected by a digital micromirror device, enabling precise and flexible spatial control without the need for photomasks. This light-guided molecular patterning strategy provides a versatile and accessible approach to increase throughput in single-molecule force spectroscopy experiments.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Force Microscopy Techniques and Applications · Molecular Junctions and Nanostructures · Nanofabrication and Lithography Techniques
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Affiliations
Program in Cellular and Molecular Medicine Boston Children's Hospital Boston Massachusetts USA
Wyss Institute For Biologically Inspired Engineering Harvard University Boston Massachusetts USA
Department of Biological Chemistry and Molecular Pharmacology Blavatnik Institute Harvard Medical School Boston Massachusetts USA
Department of Pediatrics Harvard Medical School Boston Massachusetts USA
References
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