journal article·2026-03

Dual‐Light‐Primed GSH‐Scavenging Lipid Hybrid Nanoplatform for Cascade‐Activated Photodynamic Therapy (Small 18/2026)

So‐Yeol Yoo, Jiyeon Kim, Sang Min Lee, Sangwoo Lee, Taejung Kim, JungHun Kang, Le Bich Hang Pham, Hyeonwoo Lim, Minkyung Kim, Ka‐Young Lim, Jeeyeon Lee, Jae‐Young Lee

Small· Volume 22· Issue 18
Publisher page

Abstract

Photodynamic Therapy This cover illustrates a lipid-hybridized nanoplatform (CSA-psICG/BdTT-BNBE) for cascade-activated photodynamic therapy. Guided by CSA–CD44 targeting, the system responds to dual-light irradiation (NIR and white light), triggering glutathione depletion and amplified ROS generation. This strategy enables spatiotemporally controlled activation and enhances therapeutic efficacy against tumors. More in the Research Article (e12546), Jeeyeon Lee, Jae-Young Lee, and co-workers.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Graphene and Nanomaterials Applications

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Affiliations

College of Pharmacy and Research Institute of Pharmaceutical Sciences Seoul National University Seoul Republic of Korea

Natural Products Research Institute Seoul National University Seoul Republic of Korea

References

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