DataVXSmallPaper
journal article·2026-02Open access

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles (Small 7/2026)

Yugo Araújo Martins, Louise Bondeelle, Arnaud Charles‐Antoine Zwygart, Thais Melquiades de Lima, Juliano de Paula Souza, Han Kang Tee, Fernando Chahud, Eurico de Arruda Neto, Francesco Stellacci, Renata Fonseca Vianna Lopez, Caroline Tapparel

Small· Volume 22· Issue 7
Publisher pageOpen full text
Source abstract

Abstract

Antiviral Nanoparticles In article number e07669, Yugo Araújo Martins, Caroline Tapparel, and co-workers present POSTAN, a novel antiviral nanoparticle built from biocompatible lipids that mimic heparan sulfate proteoglycans and viral lipid rafts. By hijacking the same pathways used by viruses, POSTAN dismantles their envelopes and blocks replication, demonstrating potent, broad-spectrum virucidal activity with strong translational potential.
Source: openalex_inverted_index · Quality: baseline

Research context

NanomaterialsBiomaterials

OpenAlex topics: RNA Interference and Gene Delivery · Lipid Membrane Structure and Behavior · Proteoglycans and glycosaminoglycans research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Microbiology and Molecular Medicine Faculty of Medicine University of Geneva Geneva 1211 Switzerland

Department of Pharmaceutical Sciences School of Pharmaceutical Sciences of Ribeirão Preto University of São Paulo Ribeirão Preto SP 14040‐900 Brazil

Institute of Materials École Polytechnique Fédérale de Lausanne Lausanne 1015 Switzerland

Department of Molecular and Cell Biology School of Medicine of Ribeirão Preto University of São Paulo Ribeirão Preto SP 14040‐900 Brazil

Department of Pathology School of Medicine of Ribeirão Preto University of São Paulo Ribeirão Preto SP 14040‐900 Brazil

References

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