DataVXSmallPaper
journal article·2026-03

NIR‐Triggered 3D‐Bioprinted Hydrogels for Antibacterial Skin Regeneration

Hongyu Wen, Qian Chen, Peng Zhang, Xue Yu, Jiawang Wu, Junzheng Niu, Shirui Zhang, Hui Wang, Yun Zhu, Zhaowei Teng, Lixian Mu, Xuhui Xu

Small· Volume 22· Issue 16
Publisher page
Source abstract

Abstract

ABSTRACT Near‐infrared (NIR)‐triggered hydrogen‐bonding condensation utilizing up‐conversion nanoparticles (UCNPs)‐incorporated poly of acrylic acid‐N‐vinyl‐2‐pyrrolidone (AA‐NVP) and carboxymethyl cellulose (CMC) as AA‐NVP/CMC hydrogels was explored, where the photoconversion of the corresponding fluoride UCNPs endows NIR‐mediated hydrogels fabrication for the efficient optical output. Accordingly, the developed hydrogels as bio‐ink realize a 3D‐printing in vivo. Moreover, the printed hydrogels generate reactive oxygen species (ROS) to provide potent bactericidal effects for photodynamic therapy (PDT), in conjunction with photothermal effects (PTE). It circumvents the antibiotic resistance issues associated with conventional antimicrobial agents, which fundamentally promotes skin regeneration from the inner layers of the skin to the outer layers with the synergistic antibacterial therapy.
Source: crossref · Quality: baseline

Research context

PolymersNanomaterials

OpenAlex topics: Wound Healing and Treatments · 3D Printing in Biomedical Research · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Faculty of Materials Science and Engineering Kunming University of Science and Technology Kunming Yunnan P. R. China

Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province Yunnan Provincial Department of Education Gut Microbiota Transplantation Engineering Research Center The Second Affiliated Hospital of Kunming Medical University Kunming Yunnan P. R. China

School of Basic Medical Sciences Kunming Medical University Kunming Yunnan P. R. China

School of Mechanical Engineering Chengdu University Chengdu Sichuan P. R. China

Juye County North City Hospital Heze Shandong P. R. China

Department of Dermatology and Venereology The Second Affiliated Hospital of Kunming Medical University Kunming Yunnan P. R. China

Yunnan Joint International Laboratory of Optoelectronic Materials and Devices Kunming Yunnan P. R. China

Funding

National Natural Science Foundation of China

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