journal article·2025-12Open access

One‐Step Tunable Human Hair Keratin Gradient Hydrogel with Antibacterial Activity for Tissue Engineering (Small 52/2025)

Marin Zhen Lin Yee, Yun Wei Lim, Logeshwari Muthualagu Natarajan, Bertrand Czarny, Kee Woei Ng

Small· Volume 21· Issue 52

Abstract

Tissue Engineering A gradient hydrogel made from human hair extracted keratins is formed via diffusion-mediated silver-thiolate complexation process, driven by keratin's naturally occurring high cysteine content. This single-step platform offers tuneable gradient hydrogel properties, antibacterial activity and supports extracellular matrix production in vitro. Enhanced collagen production, re-epithelization and minimal host tissue response in vivo confirm its potential for full-thickness skin tissue regeneration. More in article number 2509775, Kee Woei Ng and co-workers.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Dyeing and Modifying Textile Fibers · Hair Growth and Disorders · Skin and Cellular Biology Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore

Health Technologies Interdisciplinary Graduate Program Graduate College Nanyang Technological University Singapore 637460 Singapore

Lee Kong Chian School of Medicine Nanyang Technological University Singapore 639798 Singapore

Nanyang Environment and Water Research Institute Nanyang Technological University 1 Cleantech Loop, CleanTech One Singapore 637141 Singapore

Skin Research Institute of Singapore Clinical Sciences Building 11 Mandalay Road Singapore 308232 Singapore

References

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