DataVXSmallPaper
journal article·2025-11Open access

Noninvasive and Sensitive Biosensor for the Detection of Oral Cancer Prognostic Biomarkers (Small 47/2025)

Luciana D. Trino Albano, Daniela C. Granato, Luiz G. S. Albano, Fábio M. S. Patroni, Aline G. Santana, Guilherme A. Câmara, Davi H. S. de Camargo, Ana L. Mores, Thaís B. Brandão, Ana C. Prado‐Ribeiro, Carlos C. B. Bufon, Adriana F. Paes Leme

Small· Volume 21· Issue 47
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Source abstract

Abstract

Oral Cancer Oral cancer is often diagnosed with the presence of metastasis, which implies a significantly poor prognosis. Saliva-based liquid biopsy using biosensors targeting LTA4H, CSTB, and COL6A1 biomarkers offers high sensitivity and selectivity. In a cohort of 60 patients, machine learning analysis achieves 76% accuracy in detecting lymph node metastasis, enhancing non-invasive clinical assessments for oral cancer. More in article number 2504728, Luciana D. Trino Albano, Carlos C. B. Bufon, Adriana F. Paes Leme, and co-workers.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Oral Health Pathology and Treatment · Salivary Gland Disorders and Functions · Advanced Technologies and Applied Computing

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Center for Information Technology Renato Archer (CTI Renato Archer) Campinas São Paulo 13069‐901 Brazil

Brazilian Biosciences National Laboratory (LNBio) Brazilian Center for Research in Energy and Materials (CNPEM) Campinas São Paulo 13083‐970 Brazil

Brazilian Nanotechnology National Laboratory (LNNano) Brazilian Center for Research in Energy and Materials (CNPEM) Campinas São Paulo 13083‐970 Brazil

Dental Oncology Service Instituto do Câncer do Estado de São Paulo Faculdade de Medicina da Universidade de São Paulo (ICESP‐FMUSP) São Paulo 01246‐000 Brazil

Oral Diagnosis Department Semiology and Oral Pathology Areas Piracicaba Dental School State University of Campinas (UNICAMP) Piracicaba São Paulo 13414‐903 Brazil

Physics Department Institute of Geosciences and Exact Sciences São Paulo State University (UNESP) Rio Claro São Paulo 13506‐900 Brazil

References

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