journal article·2025-10Open access

Real‐Time Monitoring of DNA Origami‐Cell Interactions via Single Particle Tracking (Small 40/2025)

Indra Van Zundert, Elena Spezzani, Roger R. Brillas, Lars Paffen, Angelina Yurchenko, Tom F. A. de Greef, Lorenzo Albertazzi, Alessandro Bertucci, Tania Patiño Padial

Small· Volume 21· Issue 40

Abstract

DNA Origami In article number 2502496, Tania Patiño Padial and co-workers highlights real-time single-particle tracking of ligand-functionalized DNA origami nanorods interacting with cell membranes. Leveraging the spatial programmability of DNA origami, this approach enables precise interrogation of receptor-ligand binding kinetics and dynamics at the cell surface, offering new insights into nanoscale biointerfaces with high spatial and temporal resolution.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques

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Affiliations

Biomedical Engineering Department Technische Universiteit Eindhoven Het Kranenveld 14, 5612 AZ Eindhoven The Netherlands

Laboratory of Bioartificial Systems and Biosensors Department of Chemistry, Life Sciences and Environmental Sustainability University of Parma Parco Area delle Scienze, 17/A Parma 43124 Italy

References

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