Controlled Nanoconfinement in a Microfluidic Modular Bead Array Device via Elastomeric Diaphragm Collapse for Enhancing Biomolecular Binding Kinetics (Small 34/2025)
Source abstract
Abstract
Biomolecular Binding Kinetics In article number 2412474, Chia-Fu Chou, Nathan S. Swami, and co-workers presented a modular platform for controlled nanoconfinement over a large area using an elastomeric diaphragm integrated with strain sensors and microfabricated posts (≈500 nm) to enhance biomolecular binding by alternating between confinement and bulk transport for rapid DNA immobilization and screening aptamers on their binding affinities to target molecules.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Microfluidic and Capillary Electrophoresis Applications · Microfluidic and Bio-sensing Technologies · Innovative Microfluidic and Catalytic Techniques Innovation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Electrical & Computer Engineering University of Virginia Charlottesville VA 22904‐4743 USA
Institute of Physics Academia Sinica Taipei 11529 Taiwan
Research Center for Applied Science Academia Sinica Taipei 11529 Taiwan
Department of Chemistry University of Virginia Charlottesville VA 22904‐4319 USA
References
Reference metadata was not supplied for this record.