journal article·2025-12Open access

µCodes: A Universal Grid Platform for Microscale Mapping, Microscopy Navigation, and Multimodal Imaging

Aref Valipour, Jungmin Ha, Stephen N. Housley

Small· Volume 21· Issue 51

Abstract

Abstract Different imaging modalities provide unique and valuable insights into biological sample characterizations. Integration of multimodal imaging techniques is essential for comprehensive biological sample analysis. µCodes, a microgrid system designed to enhance sample navigation, alignment, and co‐registration of images obtained from various optical and electron microscopy techniques, is presented. µCodes is a platform for tracking and locating targets or cells of interest across different imaging modalities with high precision. In this paper, the design, fabrication, and implementation of µCodes are demonstrated, emphasizing their utility in imaging workflows for biological samples.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Cell Image Analysis Techniques · Single-cell and spatial transcriptomics · Advanced Fluorescence Microscopy Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Biological Sciences Georgia Institute of Technology Atlanta GA 30332 USA

School of Electrical and Computer Engineering Georgia Institute of Technology Atlanta GA 30332 USA

Scheller College of Business Georgia Institute of Technology Atlanta GA 30332 USA

George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology Atlanta GA 30332 USA

Institute for Bioengineering and Biosciences Georgia Institute of Technology Atlanta GA 30332 USA

Winship Cancer Institute Emory University Atlanta GA 30322 USA

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