journal article·2025-08Open access

Multifunctional Bioactive Dual‐Layered Nanofibrous Matrix for Effective Breast Cancer Therapy and Enhanced Wound Healing (Small 31/2025)

Sungyun Kim, Da In Jeong, Mrinmoy Karmakar, Ji‐Won Huh, Eun‐Hye Hong, Dae‐Joon Kim, Hyun‐Jeong Ko, Hyun‐Jong Cho, Ki‐Bum Lee

Small· Volume 21· Issue 31

Abstract

Breast Cancer Therapy In article number 2500717, Hyun-Jong Cho, Ki-Bum Lee, and co-workers show the anticancer effect within the tumor microenvironment following applying a dual-layered nanofibrous matrix to skin tissue after breast cancer surgery. The matrix, fabricated via electrospinning, features distinct layers that release therapeutic agents. This layered drug delivery enhances interaction with tumor cells, disrupts the cancer-supporting environment, and promotes tumor suppression with NIR laser application.
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Research context

OpenAlex topics: Graphene and Nanomaterials Applications · Electrospun Nanofibers in Biomedical Applications · Bone Tissue Engineering Materials

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Affiliations

Department of Pharmacy Kangwon National University Chuncheon Gangwon 24341 Republic of Korea

Department of Chemistry and Chemical Biology, Rutgers The State University of New Jersey 123 Bevier Road Piscataway NJ 08854 USA

Department of Regulatory Science Graduate School Kyung Hee University Seoul 02447 Republic of Korea

Institute of Regulatory Innovation through Science (IRIS) Kyung Hee University Seoul 02447 Republic of Korea

References

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