journal article·2025-07Open access

NIR‐Induced Photoswitching Hybrid DNA Nanoconstruct‐Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate (Small 26/2025)

Thanapat Pongkulapa, Ji Hye Yum, Callan D. McLoughlin, Brandon Conklin, Tomotaka Kumagai, Li Ling Goldston, Hiroshi Sugiyama, Soyoung Park, Ki‐Bum Lee

Small· Volume 21· Issue 26

Abstract

Drug Delivery Within nanomedicine, efficient control and predictable release of drug payloads are crucial to therapeutic efficacy. Opposing passive drug release, light is an attractive tool for controlling biological functions, offering unparalleled temporal and spatial precision. Leveraging this potential, the combination of photo-responsive DNA nanostructures and up-conversion nanoparticles capable of harnessing near-infrared signals presents a promising avenue for finely tuning dynamic and intricate stem cell fate regulation. More in article number 2409530, Soyoung Park, Ki-Bum Lee, and co-workers.
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Research context

OpenAlex topics: Photochromic and Fluorescence Chemistry · Advanced biosensing and bioanalysis techniques · Nanoplatforms for cancer theranostics

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Affiliations

Department of Chemistry and Chemical Biology Rutgers, The State University of New Jersey Piscataway NJ 08854 USA

Department of Chemistry Graduate School of Science Kyoto University Kitashirakawa‐oiwakecho, Sakyo‐ku Kyoto 606–8502 Japan

Institute for Integrated Cell‐Material Sciences (iCeMS) Kyoto University Yoshida‐ushinomiyacho, Sakyo‐ku Kyoto 606–8501 Japan

References

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