journal article·2025-07Open access

Nonequilibrium Self‐Assembly of Microtubules Through Stepwise Sequential Interactions of DNA (Small 26/2025)

Jakia Jannat Keya, Mousumi Akter, Yuta Yamasaki, Yoshiyuki Kageyama, Kazuki Sada, Akinori Kuzuya, Akira Kakugo

Small· Volume 21· Issue 26

Abstract

Self-Assembly The art illustrates the transfer of DNA-mediated information between microtubules (MTs) to initiate assembly formation. A green, DNA-modified MT is portrayed as being locked by a chain, which is subsequently unlocked or activated through interaction with a blue, DNA-modified MT. Here, DNA serves as a “physical key” that facilitates the activation of the green DNA-modified MT. The blue DNA-modified MT symbolizes the carrier of information. Upon unlocking, the chain is removed, allowing the green MT to bind with the red MT, thereby completing the assembly process. In article number 2408364, Akinori Kuzuya, Akira Kakugo, and co-workers.
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Research context

OpenAlex topics: Molecular Communication and Nanonetworks

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Affiliations

Department of Cell and Developmental Biology University of Michigan Medical School Ann Arbor MI 48109 USA

Department of Mechanical Engineering University of Michigan Ann Arbor MI 48108 USA

Department of Chemistry and Materials Engineering Kansai University Osaka 564‐8680 Japan

Graduate School of Chemical Sciences and Engineering Hokkaido University Sapporo 060‐0810 Japan

Faculty of Science Hokkaido University Sapporo 060‐0810 Japan

Department of Physics Kyoto University Kyoto 606‐8224 Japan

References

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