Utilizing Two Electrokinetic Techniques on a Single Device for Detection of Extracellular Vesicle‐Associated Protease Activity (Small 24/2025)
Source abstract
Abstract
Protease Activity Two different types of electrokinetic forces can be generated on the same electrode array to manipulate both nanoparticles and small molecules separately. This is used to quantify protease activity of cancer-derived extracellular vesicle nanoparticles for clinical diagnostics. The first force is dielectrophoresis that attracts extracellular vesicle nanoparticles to the circular electrode edges. The second force is electrophoresis that draws charged molecular byproducts from protease activity to the electrode centers. More in article number 2404457, Stuart D. Ibsen and co-workers.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Lipid Membrane Structure and Behavior · Microbial Inactivation Methods · Microfluidic and Bio-sensing Technologies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Cancer Early Detection Advanced Research Center Knight Cancer Institute Oregon Health & Science University Portland OR 97201 USA
Department of Biomedical Engineering School of Medicine Oregon Health & Science University Portland OR 97201 USA
Department of NanoEngineering University of California San Diego San Diego CA 92093 USA
References
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