Morpholine Anchored Fluorogenic Toolkit: Unveiled Disease Allied Protein Fibrillation in Lysosomal Compartment of Live‐Cell and Drosophila Models (Small 21/2025)
Source abstract
Abstract
Neurodegenerative Diseases Protein aggregation is a hallmark of neurodegenerative diseases. Far-red emissive SC-4mor selectively detects protein aggregates in lysosomes of live cells and Drosophila models (neurodegenerative and non-neurodegenerative disease models). Ability of SC-4mor to cross the blood-brain barrier in mice model highlights its potential for investigating the pathogenesis and progression of protein aggregation-related diseases in the near future. More in article number 2404008, Monalisa Mishra, Apurba Lal Koner, and co-workers.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Cellular transport and secretion · Lysosomal Storage Disorders Research · Alzheimer's disease research and treatments
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Affiliations
Bionanotechnology Laboratory Department of Chemistry Indian Institute of Science Education and Research Bhopal Bhopal Bypass Road, Bhauri Bhopal Madhya Pradesh 462066 India
Neural Developmental Biology Laboratory Department of Life Science National Institute of Technology (NIT) Rourkela Odisha 769008 India
Department of Biological Sciences Indian Institute of Science Education and Research Bhopal Bhopal Bypass Road, Bhauri Bhopal Madhya Pradesh 462066 India
References
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