pH‐Responsive DNA‐Functionalized Liquid Metal–Organic Frameworks (L‐MOFs) as Molecular Sponges for Ultrasensitive and Label‐Free SERS Detection of Folic Acid (Small 21/2025)

Xu Liu; Liliia Glazutdinova; Guangrun Wu; Wenxu Yang; Hongbo Liu; Yifu Shen; Siyao Zhang; Jing Wu; Haoyu Ji; Lixin Gao; Xinlu Gao; Jiayi Zhao; Yang Li; Yu Liu

doi:10.1002/smll.202570166

journal article·2025-05Open access

pH‐Responsive DNA‐Functionalized Liquid Metal–Organic Frameworks (L‐MOFs) as Molecular Sponges for Ultrasensitive and Label‐Free SERS Detection of Folic Acid (Small 21/2025)

Xu Liu, Liliia Glazutdinova, Guangrun Wu, Wenxu Yang, Hongbo Liu, Yifu Shen, Siyao Zhang, Jing Wu, Haoyu Ji, Lixin Gao, Xinlu Gao, Jiayi Zhao, Yang Li, Yu Liu

Small· Volume 21· Issue 21

Publisher page Open full text

Source abstract

Abstract

SERS Sensing Platform In article number 2412267, Yang Li, Yu Liu, and co-workers have innovatively proposed a pH-responsive, hotspot-tunable MOFs-like three-dimensional SERS sensing platform by utilizing DNA-mediated self-assembly of silver nanoparticles. Adjustable DNA chains according to target molecules, allowing for customized hotspot locations. Under alkaline conditions, this platform demonstrates excellent sensing performance, showing remarkable detection limits and stability in the detection of folic acid.

Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Advanced Nanomaterials in Catalysis · Advanced biosensing and bioanalysis techniques · Nanocluster Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Laboratory Medicine at The Fourth Affiliated Hospital Harbin Medical University Harbin 150086 China

Research Center for Innovative Technology of Pharmaceutical Analysis (State Key Laboratory of Frigid Zone Cardiovascular Diseases) College of Pharmacy Harbin Medical University Heilongjiang 150081 P. R. China

School of Physical Science and Technology Nantong University No. 9, Seyuan Road Nantong Jiangsu 26019 P. R. China

Department of Pharmacy at The Second Affiliated Hospital Harbin Medical University Harbin 150081 China

Research Unit of Health Sciences and Technology (HST) Faculty of Medicine University of Oulu Oulu 90220 Finland

References

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