Localized Microrobotic Delivery of Enzyme‐Responsive Hydrogel‐Immobilized Therapeutics to Suppress Triple‐Negative Breast Cancer (Small 18/2025)
Source abstract
Abstract
Breast Cancer In article number 2408813, Meysam Keshavarz, Guang-Zhong Yang, and co-workers present a microrobotic platform for the localized delivery of enzyme-responsive hydrogels, designed to release chemotherapeutics within the tumor microenvironment. Utilizing magnetic actuation for precise localization, this system enables sustained drug release, achieving significant tumor reduction and metastasis suppression in a murine model of triple-negative breast cancer, underscoring its potential for broader oncological applications.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Micro and Nano Robotics · Microtubule and mitosis dynamics · Molecular Communication and Nanonetworks
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Affiliations
Institute of Medical Robotics, School of Biomedical Engineering Shanghai Jiao Tong University Shanghai 200240 China
The Hamlyn Centre, Institute of Global Health Innovation Imperial College London London South Kensington SW7 2AZ UK
Department of Metabolism, Digestion, and Reproduction, Faculty of Medicine Imperial College London London SW7 2AZ UK
References
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