journal article·2025-04Open access

Self‐Cascade API Nanozyme for Synergistic Anti‐Inflammatory, Antioxidant, and Ferroptosis Modulation in the Treatment of Corneal Neovascularization (Small 17/2025)

Hongwei Wang, Yang Yang, Huimin Yu, Li Ma, Xia Qi, Junpeng Qu, Xiaoyu Zhang, Na Li, Shengqian Dou, Xiaoxue Liu, Chao Wei, Hua Gao

Small· Volume 21· Issue 17

Abstract

Corneal Neovascularization In article number 2407751, Hua Gao and co-workers designed a self-cascade active pharmaceutical ingredient nanozyme to combat corneal neovascularization, a condition that can severely impair vision. The nanozyme demonstrates the ability to inhibit reactive oxygen species, reduce inflammatory cytokines, and modulate ferroptosis, highlighting its potential as a safe and effective treatment for ocular inflammatory diseases.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Selenium in Biological Systems · Sulfur Compounds in Biology

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory Cultivation Base Shandong Key Laboratory of Eye Diseases Eye Institute of Shandong First Medical University Qingdao 266071 China

School of Ophthalmology Shandong First Medical University Jinan 250062 China

The Affiliated Women's and Children's Hospital of Ningbo University Ningbo 315000 China

Medical College Qingdao University Qingdao 266073 China

Eye Hospital of Shandong First Medical University Jinan 250117 China

References

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