journal article·2025-02Open access

Amphiphilic Gelator‐Based Shear‐Thinning Hydrogel for Minimally Invasive Delivery via Endoscopy Catheter to Remove Gastrointestinal Polyps (Small 8/2025)

Harshil Dave, Hitasha Vithalani, Hemant Singh, Indu Yadav, Abhinav Jain, Ankit Pal, Nishant Patidar, Archana Navale, Mukesh Dhanka

Small· Volume 21· Issue 8

Abstract

Polymeric Hydrogels In article number 2405508, Mukesh Dhanka and co-workers highlights the development of an endoscopically injectable, self-assembled hydrogel derived from plant-based diglycerol monostearate, an amphiphilic molecule. This hydrogel encapsulates the hydrophilic methylene blue and the blood clotting agent 6-ACA. The platform exhibits shear-thinning properties, enabling smooth injection through a long endoscopy catheter to form a durable submucosal cushion. This cushion facilitates the effective removal of pre-cancerous tumors from the gastrointestinal tract.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Gastrointestinal disorders and treatments · Gastrointestinal Tumor Research and Treatment · Gastric Cancer Management and Outcomes

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Affiliations

Department of Biological Sciences and Engineering Indian Institute of Technology Gandhinagar Gandhinagar Gujarat 382355 India

Gastro1 Hospital Ahmedabad Gujarat 380060 India

Muljibhai Patel Urological Hospital Nadiad Gujarat 38700 India

Parul Institute of Pharmacy Parul University Vadodara Gujarat 391760 India

References

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