Combining Top‐Down and Bottom‐Up: An Open Microfluidic Microtumor Model for Investigating Tumor Cell‐ECM Interaction and Anti‐Metastasis (Small 9/2025)
Source abstract
Abstract
Microtumor Model By leveraging an exclusive liquid repellency (ELR)-underoil open microfluidic system (UOMS), an open microfluidics-based microtumor model for studying tumor cell migration in an in vivo-like confined space and interaction with extracellular matrix was developed. The UOMS microtumor model was tested with the anti-metastatic effect of incyclinide, showing the potential as an ex vivo platform for micrometastasis study and anti-metastasis drug screening. More in article number 2402499, Chao Li, Yingguang Liu, and co-workers.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: 3D Printing in Biomedical Research · Cancer Cells and Metastasis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Carbone Cancer Center University of Wisconsin‐Madison Madison WI 53792 USA
Department of Biomedical Engineering University of Wisconsin‐Madison Madison WI 53706 USA
College of Osteopathic Medicine Liberty University Lynchburg VA 24502 USA
Department of Biochemistry University of Wisconsin‐Madison Madison WI 53706 USA
Department of Integrative Biology University of Wisconsin‐Madison Madison WI 53706 USA
References
Reference metadata was not supplied for this record.