Advancing COVID‐19 Diagnosis: Enhancement in SERS‐PCR with 30‐nm Au Nanoparticle‐Internalized Nanodimpled Substrates (Small 46/2024)
Source abstract
Abstract
Molecular Diagnostic Systems Using an Au nanoparticles-Au nanodimples (AuNPs-AuNDPs) substrate, in article number 2403672, Sang-Woo Joo, Sung-Gyu Park, Jaebum Choo, and co-workers developed a highly sensitive surface-enhanced Raman scattering (SERS)-polymerase chain reaction molecular diagnostic assay platform capable of detecting 105 copies/μL of the SARS-CoV-2 target gene with a minimal number of thermocycles. These results are expected to ultimately lay the foundation for developing SERS-based amplification-free molecular diagnostic systems.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: SARS-CoV-2 detection and testing · Biosensors and Analytical Detection · Advanced Nanomaterials in Catalysis
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Affiliations
Department of Chemistry Chung‐Ang University Seoul 06974 South Korea
Nano‐Bio Convergence Department Korea Institute of Materials Science (KIMS) Changwon 51508 South Korea
Department of Chemistry Soongsil University Seoul 06978 South Korea
References
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