Study of Iron Complex Photosensitizer with Hollow Double‐Shell Nano Structure Used to Enhance Ferroptosis and Photodynamic Therapy (Small 30/2024)
Source abstract
Abstract
Ferroptosis Therapy In article number 2309086, Baofen Ye, Yue Wang, Ran Yan, and co-works developed a nanophotosensitizer IR783-Fe@MnO2-HA, a hyaluronic acid-encapsulated iron complex photosensitizer with a hollow double-shell nanostructure. This nanophotosensitizer targets the CD44 receptor, releases Fe3+ and IR783 in acidic conditions, enhances the Fenton reaction, induces ferroptosis, and exhibits tumor-targeting ability and efficient tumor inhibition in vivo due to the synergistic effects of photodynamic and ferroptosis antitumor therapies.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoplatforms for cancer theranostics
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Affiliations
Key Laboratory of Biomedical Functional Materials, School of Science China Pharmaceutical University Nanjing 211198 China
Electron Microbeam Analysis Laboratory University of Michigan Ann Arbor MI 48109 USA
References
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