journal article·2024-06Open access

Transepithelial Electrical Impedance Increase Following Porous Substrate Electroporation Enables Label‐Free Delivery (Small 25/2024)

Justin R. Brooks, Tyler C. Heiman, Sawyer R. Lorenzen, Ikhlaas Mungloo, Siamak Mirfendereski, Jae Sung Park, Ruiguo Yang

Small· Volume 20· Issue 25

Abstract

Label-Free Electroporation In article number 2310221, Ruiguo Yang and co-workers propose a porous substrate-based electroporation platform for high-throughput and controlled delivery using commercially available cell culture inserts. Transepithelial electrical impedance (TEEI) monitoring was incorporated to the platform, providing insight into the intermediate steps of the electroporation process. The TEEI changes were found to correlate with delivery efficiency, enabling label-free delivery.
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Research context

OpenAlex topics: Microbial Inactivation Methods · Electrospun Nanofibers in Biomedical Applications

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Affiliations

Department of Mechanical and Materials Engineering University of Nebraska‐Lincoln Lincoln NE 68588 USA

Nebraska Center for Integrated Biomolecular Communication University of Nebraska‐Lincoln Lincoln NE 68588 USA

Department of Biomedical Engineering Michigan State University East Lansing MI 48824 USA

Institute for Quantitative Health Science and Engineering (IQ) Michigan State University East Lansing MI 48824 USA

References

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