Step‐By‐Step Standardization of the Bottom‐Up Semi‐Automated Nanocrystallization of Pharmaceuticals: A Quality By Design and Design of Experiments Joint Approach (Small 25/2024)
Source abstract
Abstract
Nanosized Drug Crystals In article number 2306054, Yohann Corvis and co-workers describe a combined Quality-by-Design/Design of Experiments approach to determine the optimal experimental parameters for formulating curcumin nanocrystals that are uniform in size and stable. The authors used a standardized, reproducible, and robust nanocrystallization protocol for the preparation of therapeutic organic nanocrystals employing a semi-automated solvent-antisolvent precipitation method. The TICE department of Université Paris Cité is acknowledged for their assistance with the cover picture.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Crystallization and Solubility Studies · Drug Solubulity and Delivery Systems · Biosimilars and Bioanalytical Methods
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
CNRS INSERM Chemical and Biological Technologies for Health Group (UTCBS) Université Paris Cité Paris F‐75006 France
Drug Development Laboratory LR12ES09 Faculty of Pharmacy University of Monastir Monastir 5060 Tunisia
Institute of Macromolecular Chemistry Czech Academy of Sciences Heyrovského náměstí 2 Prague CZ‐162 06 Czech Republic
EuroAPI France Particle Engineering and Sizing Department Vertolaye F‐63480 France
References
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