Rationally Designed Functionalization of Single‐Walled Carbon Nanotubes for Real‐Time Monitoring of Cholinesterase Activity and Inhibition in Plasma (Small 24/2024)
Source abstract
Abstract
Real-Time Monitoring of Enzymes In article number 2309481, Gili Bisker and co-workers utilize near-infrared fluorescent single-walled carbon nanotubes (SWCNTs) to monitor cholinesterase activity and inhibition in blood plasma. The SWCNTs are strategically functionalized with a substrate of cholinesterase, namely, myristoylcholine. Enzymatic cleavage of myristoylcholine results in a detectable modulation of the SWCNT fluorescence intensity, while the lack of fluorescence response indicates cholinesterase inhibition.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Cholinesterase and Neurodegenerative Diseases · Electrochemical sensors and biosensors
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Affiliations
Department of Biomedical Engineering Faculty of Engineering Tel Aviv University Tel Aviv 6997801 Israel
Center for Physics and Chemistry of Living Systems Tel Aviv University Tel Aviv 6997801 Israel
Center for Nanoscience and Nanotechnology Tel Aviv University Tel Aviv 6997801 Israel
Center for Light‐Matter Interaction Tel Aviv University Tel Aviv 6997801 Israel
References
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