journal article·2023-10Open access

Synergistic Enzyme‐Mimetic Catalysis‐Based Non‐Thermal Sonocavitation and Sonodynamic Therapy for Efficient Hypoxia Relief and Cancer Ablation (Small 42/2023)

Min Liao, Fan Chen, Lin Chen, Zihe Wu, Jianbo Huang, Houqing Pang, Chong Cheng, Zhe Wu, Lang Ma, Qiang Lu

Small· Volume 19· Issue 42

Abstract

Cavitation Ablation In article number 2302744, Zhe Wu, Lang Ma, Qiang Lu, and co-workers develop an Mn-coordinated polyphthalocyanine sonocavitation agent that consists of Mn-phthalocyanine as the catalytic sites and the conjugated layer-stacked polyphthalocyanine network as the acoustic response group, which will help deepen the understanding of non-thermal cavitation ablation histotripsy and the sonodynamic mechanisms with high reactive oxygen species (ROS) production for solid tumor ablation.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Supramolecular Chemistry and Complexes

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Affiliations

Department of Medical Ultrasound Frontiers Science Center for Disease‐Related Molecular Network, West China Hospital Sichuan University Chengdu 610041 China

College of Polymer Science and Engineering State Key Laboratory of Polymer Materials Engineering Sichuan University Chengdu 610065 China

School of Life Science and Technology University of Electronic Science and Technology of China Chengdu 610054 China

Department of Ultrasound West China Second University Hospital Sichuan University Chengdu 610041 China

References

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