journal article·2023-09Open access

Spontaneous Formation of Uniform Cell‐Sized Microgels through Water/Water Phase Separation (Small 38/2023)

Mayu Shono, Gen Honda, Miho Yanagisawa, Kenichi Yoshikawa, Akihisa Shioi

Small· Volume 19· Issue 38

Abstract

Uniform Cell-Sized Microgels In article number 2302193, Miho Yanagisawa, Akihisa Shioi, and co-workers report on spontaneous formation of uniform cell-sized microgels inside a glass capillary. By adapting aqueous polymer solution containing DNA, droplets entrapping DNA are generated in a self-organized manner through micro phase-separation, and these droplets are transformed into gel state by decreasing the temperature. The microgels are easily extruded into bulk water, maintaining their size.
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Research context

OpenAlex topics: Innovative Microfluidic and Catalytic Techniques Innovation

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Affiliations

Department of Chemical Engineering and Materials Science Doshisha University 6100321 Kyoto Japan

Komaba Institute for Science Graduate School of Arts and Sciences The University of Tokyo Komaba 3‐8‐1 Meguro Tokyo 153‐8902 Japan

Center for Complex Systems Biology Universal Biology Institute The University of Tokyo Komaba 3‐8‐1 Meguro Tokyo 153‐8902 Japan

Graduate School of Science The University of Tokyo Hongo 7‐3‐1 Bunkyo Tokyo 113‐0033 Japan

Faculty of Life and Medical Sciences Doshisha University 6100394 Kyoto Japan

Center for Integrative Medicine and Physics Institute for Advanced Study Kyoto University 606 8501 Kyoto Japan

References

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