journal article·2023-08Open access

Dual‐Wave Acoustofluidic Centrifuge for Ultrafast Concentration of Nanoparticles and Extracellular Vesicles (Small 35/2023)

Povilas Dumčius, Roman Mikhaylov, Xiaoyan Zhang, Matthew Bareford, Mercedes Stringer, Rachel Errington, Chao Sun, Esperanza Gonzalez, Tomaš Krukovski, Juan M Falcon‐Perez, Dongfang Liang, Yong‐Qing Fu, Aled Clayton, Xin Yang

Small· Volume 19· Issue 35

Abstract

Surface Acoustic Waves The acoustofluidic concentration of extracellular vesicles (ACEV) technique leverages the power of dual acoustic waves, creating a single vortex stream within a droplet that serves to concentrate extracellular vesicles effectively. This state-of-the-art method, with immense potential for advancing cancer research, employs a carefully positioned thin-film circuit board on a piezoelectric substrate. These components are designed to generate the optimal acoustic field, enabling the efficient and precise concentration of these vital nanostructures, which play significant roles in cancer progression and intercellular communication. More details can be found in article number 2300390 by Xin Yang and co-workers.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Biosensors and Analytical Detection · Innovative Microfluidic and Catalytic Techniques Innovation · Extracellular vesicles in disease

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Affiliations

Department of Electrical and Electronic Engineering School of Engineering Cardiff University Cardiff CF243AA UK

Tissue Micro‐Environment Group Division of Cancer & Genetics School of Medicine Cardiff University Cardiff CF144XN UK

School of Life Sciences Northwestern Polytechnical University Xi'an P. R. China

Exosomes Laboratory CIC bioGUNE‐BRTA CIBERehd Bizkaia Technology Park Bilbao 48160 Spain

Department of Electrical Engineering and Sensor Technology Institute of Engineering Hanze University Groningen AS Groningen 119747 Netherlands

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas Y Digestivas (CIBERehd) Madrid 28029 Spain

IKERBASQUE Basque Foundation for Science Bilbao 48011 Spain

Department of Engineering University of Cambridge Cambridge CB2 1PZ UK

Faculty of Engineering and Environment Northumbria University Newcastle upon Tyne NE1 8ST UK

References

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