Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects (Small 12/2023)
Source abstract
Abstract
Enhancement of Radiation Therapy Effects Liposome-based nanoparticles encapsulating transcrocetin (NP TSC) act as therapeutic radiosensitizer. In article number 2205961, Alexandre Detappe and co-workers perform a study on mouse to confirm their ability to reoxygenate triple negative breast cancer tumors for up to 48h. This reoxygenation effect leads to normalisation of the vasculature which enhances the radiation therapy effects.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Cancer, Lipids, and Metabolism · Cancer Treatment and Pharmacology · Flavonoids in Medical Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institut de Cancérologie Strasbourg Europe Strasbourg France
Ex Vivo Cancer Pharmacology Centre Biodiscovery Institute Translational Medical Sciences School of Medicine University of Nottingham UK
Sir Peter Mansfield Imaging Centre School of Medicine and School of Chemistry University of Nottingham UK
Strasbourg Drug Discovery and Development Institute (IMS) Strasbourg France
References
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