journal article·2023-02Open access

A Multilayered Mesoporous Gold Nanoarchitecture for Ultraeffective Near‐Infrared Light‐Controlled Chemo/Photothermal Therapy for Cancer Guided by SERS Imaging (Small 6/2023)

Bohan Yin, Willis Kwun Hei Ho, Xinyue Xia, Cecilia Ka Wing Chan, Qin Zhang, Yip Ming Ng, Ching Ying Katherine Lam, James Chung Wai Cheung, Jianfang Wang, Mo Yang, Siu Hong Dexter Wong

Small· Volume 19· Issue 6

Abstract

Chemo/Photothermal Therapy for Cancer Guided by SERS Imaging In article number 2206762, Mo Yang, Siu Hong Dexter Wong, and co-workers develop a multilayered mesoporous gold nanoarchitecture labeled with Raman reporters for ultraeffective surface-enhanced Raman scattering (SERS) imaging-guided synergistic therapy toward cancer. This nanoplatform enables efficient xenograft tumor model targeting with sensitive SERS imaging in vitro and in vivo for identifying the tumor cells and optimal therapeutic time point, thereby achieving the highest therapeutic outcome of noninvasive near-infrared triggered photothermal therapy and hyperthermia enhanced chemotherapy.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Extracellular vesicles in disease · Gold and Silver Nanoparticles Synthesis and Applications

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Affiliations

Department of Biomedical Engineering The Hong Kong Polytechnic University Kowloon Hong Kong 999077 China

Department of Physics The Chinese University of Hong Kong Shatin Hong Kong 999077 China

Department of Surgery The Chinese University of Hong Kong Shatin Hong Kong 999077 China

Research Institute for Sports Science and Technology The Hong Kong Polytechnic University Kowloon Hong Kong 999077 China

References

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