Native Planar Asymmetric Suspended Membrane for Single‐Molecule Investigations: Plasma Membrane on a Chip (Small 51/2022)
Source abstract
Abstract
Single-Molecule Investigations In article number 2205567, Sathish Ramakrishnan and co-workers present a tunable silicon-based platform that supports suspended lipid membranes (SLIM) to interrogate membrane protein assembly and dynamics using total internal reflection fluorescence (TIRF) microscopy. By generating bilayers from giant plasma membrane vesicles derived from different cell types, it is possible to capture fast dynamics of protein function on the inner leaflet of cells while retaining native lipid architecture and asymmetry.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Lipid Membrane Structure and Behavior
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Affiliations
Nanobiology Institute Yale University School of Medicine West Haven CT 06516 USA
Department of Cell Biology Yale University School of Medicine New Haven CT 06520 USA
Department of Pathology Yale University School of Medicine New Haven CT 06520 USA
Department of Neurology Yale University School of Medicine New Haven CT 06520 USA
References
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